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Modern spectroscopic methods make it possible to determine the structure of most low molecular weight natural products relatively quickly. Frequently only milligram quantities of the compound are required. It is thus incumbent on the natural products chemist involved in structure determination to utilize this ability to address problems beyond that of structure elucidation. In recent years we have been studying the metabolites of some fungi which cause, or cure, plant diseases, in an attempt to more fully understand the etiology of the diseases and perhaps to facilitate control strategies. Plant diseases which we have studied include the blue stain disease of pine, Scleroderris canker, black spot of canola, the American leaf spot disease of coffee, and the fairy ring mushroom problem. During these studies a variety of new natural products have been discovered. Some of the "chemically" more interesting new compounds will be discussed, and the phytotoxins associated with some of the plant diseases mentioned will be identified.
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