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Poly-u directed incorporation of phenylalanine into ribosomes of growing rat tissues

MM

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M.R.V. Murthy

Résumé du colloque

Ribosomes were prepared from brains and livers of rats at different periods of growth and the incorporation of phenylalanine-C14 was measured in the presence and in the absence of added poly-u. The incorporation into brain ribosomes increased 4-5 folds on addition of poly-u. The increase was less pronounced in liver ribosomes at any of the developmental stages tested. Poly-u induced incorporation into either of the two ribosome preparations was enhanced greatly by such pretreatments as preincubation of ribosomes, mild digestion with RNAase or treatment with EDTA. The significance of these results will be discussed.

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host icon Hôte : Université d’Ottawa

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