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Synthesizing Various Nanoparticles towards Biomedical Applications

Dongling Ma
Sophie Tan
Zygmunt J. Jakubek
Benoît Simard
DM

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Dongling Ma

Résumé de la communication

Dye-doped silica nanoparticles (NPs) and semiconductor nanocrystals, i.e. quantum dots (QDs), offer great potential as a new generation of biomarkers for highly sensitive detection down to single-molecule level. Herein, we present our work on the controlled synthesis of these two types of NPs. I will also briefly talk about the development of multifunctional NPs that integrate photoluminescence and superparamagnetism into a single nano-architecture. Several types of dyes, which have varying molecular weights and are capable of forming different bonding with silica networks, have been exploited to form dye-doped silica NPs. It is found that these dyes show quite different photophysical responses after encapsulation. We further examined their structural stability under different conditions. In contrast to the majority of research on visible-emitting QDs, much less work has been reported for QDs with near-infrared emission, which are more suitable for in vivo imaging. We have synthesized PbS QDs with narrow and strong absorption ranging from 1100-1600 nm. Their nucleation and growth mechanism has been investigated. For the multifunctional NPs, we have developed a new two-step approach to gain a better control over nanostructures than conventional Stöber or reverse microemulsion methods used independently. Their magnetic and photophysical properties will be reported herein.

Résumé du colloque

La qualité de la recherche effectuée par les professeurs invités dans le cadre de ce colloque est de haut niveau et permettra de favoriser les échanges entre les différents groupes de recherche en biophotonique au Québec.

Contexte

Section :
Biophotonique : développements et applications
news icon Thème du colloque :
Biophotonique : développements et applications
manager icon Responsables :
François Légaré
host icon Hôte : Institut national de la recherche scientifique

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Thème du colloque :

Biophotonique : développements et applications
Synthesizing Various Nanoparticles towards Biomedical Applications
Dongling Ma
Synthesizing Various Nanoparticles towards Biomedical Applications
Dongling Ma
Synthesizing Various Nanoparticles towards Biomedical Applications
Dongling Ma