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We tried to solve both the forward and inverse problems of electrocardiography to understand better the relationship between epicardial and body surface potentials in specific cases of controlled acute ischemia produced during coronary angioplasty. In the forward solutions, we simulated ischemic conditions in an anisotropic realistically shaped model of the human ventricles. The heart’s primary electric sources were determined according to the anisotropic bidomain theory; the secondary sources, arising due to boundary conditions, were evaluated by the boundary-element method. As a result, we obtained simulated body-surface potentials that could be compared with corresponding measurements in patients undergoing coronary angioplasty. In …
