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The tonsil of the soft palate in pigs is a secondary lymphoid tissue that provides a first line of defense against foreign antigens entering by the mouth or nares, but paradoxically, it is also the site of colonization and entry of many bacterial and viral pathogens. Our initial understanding of a limited number of specific microbes present at this site came from culture-based studies. Recently, however, 16S rRNA gene based studies have revealed that Proteobacteria and Firmicutes predominate this site with Actinobacillus, Alkanindiges, Fusobacterium, Haemophilus, Pasteurella, Veillonella, Peptostreptococcus, and Streptococcus making up the majority of reads. In our current studies …
